Amniocentesis Test
Amniotic Fluid is the fluid that surrounds the baby inside the uterus. The baby sheds cells into the amniotic fluid and these cells can be used to ascertain the genetic makeup of the baby. This fluid can be withdrawn by inserting a thin needle under ultrasound guidance into the uterus and this process is known as Amniocentesis.
Reasons to perform the procedure:
- Following a positive prenatal screening test like Dual, Quadruple Marker or NIPT (Non-Invasive prenatal testing).
- History of having a previous baby with a chromosomal condition like Down syndrome
- Family history/ parents affected with a specific genetic condition
- High maternal age: >35 yrs
- To evaluate the baby for an infection
- Therapeutic, in case of polyhydramnios, to reduce the volume of amniotic fluid.
Optimal time for the procedure:
- 16-18 weeks is the preferred time.
- Disclose and discuss all medications before going for the procedure. Some medications might have to be discontinued before the procedure.
- Consider asking someone to accompany you to the appointment for emotional support and to drive you back.
- You will need to sign a consent form before the procedure.
What to expect after the procedure:
- Transient uterine cramping, spotting and vaginal loss of a few drops of amniotic fluid can occur immediately after the procedure.
- However, seek medical advice if you have persistent fluid leaking from the vagina, heavy vaginal bleeding, severe abdominal pain or fever.
Possible complications
- Miscarriage (1 in 300 to 1 in 500). It usually occurs within the first 5 days of the procedure Risk is higher if
- The procedure is done before 15 weeks of pregnancy
- BMI>40kg/m2
- Previous episode of vaginal bleeding during current pregnancy
- History of previous spontaneous abortions
- Leaking amniotic fluid: Rare
- Infection: Rare
- IInfection transmission from mother to baby (If the mother has Hepatitis C or Toxoplasmosis)
- Needle injury: Rare
When can you expect the results:
- 2-3 weeks for karyotyping
- 3-5 days for QF-PCR
